I have to agree. There's a lot of energy that goes into digestion. I've gone a day without eating or drinking, and then another with water. It sucks going into a fast but I've been in no hurry to eat on the second day. I do believe in fasting.
I’m a fan of the Paul saladino and recently got this in one of his email newsletters where he was talking about questionable “biohacks”. I’m not saying it’s right or wrong but just thought I’d post it here
1: Caloric Restriction/Fasting
This whole thing stemmed from monkey studies that supposedly showed lifespan boosting benefits...
Completely misinterpreted.
The University of Wisconsin study showing lifespan extension was feeding the monkeys… monkey chow - basically the equivalent of Cheerios and vegetable oil!
But guess what happened when they replicated that same experiment with a species-appropriate diet? NO life extension benefit. Zero.
Conclusion: eating less garbage makes you live longer… NOT less calories.
This is the trap people fall into.
Because when you restrict real food, you run the risk of tanking hormones, inducing frailty and sarcopenia, ruining thyroid function and A LOT more.
"But Paul, the longevity experts practice caloric restriction!"
Right. Those same "longevity experts" use TRT and pop 100+ pills just to function normally... hardly optimal 🙄
As for fasting…
The literature around fasting and autophagy isn't as clear as I once thought…
Your body is ALWAYS doing autophagy - constantly recycling proteins whether you're eating or not.
You induce autophagy through sleeping (occurs during NREM/REM stages), exercise, and sauna - WITHOUT starving yourself.
Even eating glucose can trigger autophagy!
But here's what really concerns me: there's evidence IF could induce NEGATIVE cardiac remodeling - your heart literally gets weaker!
In humans, time-restricted eating under 8 hours/day was linked with a 91% higher risk of cardiovascular death, based on NHANES data analysis reported in 2024.
To make matters worse…
Emerging evidence suggests it may even push you toward cancer-related pathways (not conclusive yet, but concerning).
Bottom line: It’s more appropriate to give your body signals of ABUNDANCE through consistent, high-quality nutrition - versus piling on more stress through artificial scarcity.